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  • Title: [The role of endotoxin in the bronchial hyperreactivity formation].
    Author: Chen JX, Wu HX, Wang Y.
    Journal: Zhonghua Yi Xue Za Zhi; 1994 Jan; 74(1):38-9, 64. PubMed ID: 8032984.
    Abstract:
    Endotoxin was as a pathogen to investigate its effects on bronchial hyperreactivity formation. The latent periods of guinea pigs inhaled histamine and PD2 value of isoproterenol were markedly decreased 4 days after the intraperitoneal injection of endotoxin 1 mg/kg, meanwhile PD2 value of histamine and histamine levels of lung tissue and plasma were increased significantly. These results indicate that endotoxin is a very important factor in the infection induced bronchial hyperreactivity.
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