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  • Title: Differential action of staphylococcal alpha-toxin on young and old erythrocytes.
    Author: Kantor L, Fackrell HB.
    Journal: Gerontology; 1994; 40(1):1-7. PubMed ID: 8034197.
    Abstract:
    Band 3 of rabbit erythrocytes is a binding site for staphylococcal alpha-toxin. Young erythrocytes have a functionally intact band 3 of 100 kD that is hydrolysed as the cells age into a 35-kD fragment. Consequently, aging of erythrocytes renders them more resistant to the action of the toxin. Thus the age of a blood sample will reduce the sensitivity of the hemolytic assay and contribute to the variation of this assay.
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