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  • Title: A seroprevalence study of herpes virus type 2 infection in Israeli women: implications for routine screening.
    Author: Isacsohn M, Bar On E, Yaeger Y, Smetana Z, Weiner D, Slater PE.
    Journal: Isr J Med Sci; 1994; 30(5-6):379-83. PubMed ID: 8034487.
    Abstract:
    The aim of the study was to obtain data on the prevalence of herpes simplex virus type 2 (HSV-2) in selected populations of women and to identify groups that might benefit from routine prenatal screening. The prospective seroprevalence study was performed in 1,921 women in Israel during the period 1986-90. Four different population groups of women 17-60 years old were included. Groups 1 and 2 comprised 1,214 healthy female government employees and kibbutz and moshav residents, and Groups 3 and 4 comprised 707 Jewish and non-Jewish women with gynecological complaints. HSV-2 antibody in the sera were studied by the microneutralization method. In the healthy women (groups 1 and 2), the prevalence of antibodies to HSV-2 was 2-3%. Genital HSV-2 asymptomatic shedding was 1%. In the women with gynecological complaints (groups 3 and 4) the prevalence of antibodies to HSV-2 was 10% in Jewish and 16% in non-Jewish women. These data support the conclusion that there is no justification for routine prenatal HSV-2 screening in Israel in a healthy female population.
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