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  • Title: [Clinical effectiveness, adverse effects and complications of intravenous administration of ATP in paroxysmal tachycardia].
    Author: Lipnitskiĭ TN, Denisiuk VI, Randin AG, Stepaniuk AV, Muravitskiĭ OV.
    Journal: Kardiologiia; 1993; 33(1):23-5. PubMed ID: 8035538.
    Abstract:
    Forty patients with paroxysmal tachycardias were studied. After intravenous bolus administration of ATP, 10-20 mg sinus rhythm restored in 24 patients with nodal reciprocal tachycardia or Wolff-Parkinson-White syndrome. In patients with ventricular tachycardia, antidromal paroxysmal tachycardia in the presence of the Wolff-Parkinson-White syndrome and atrial flutter, bolus administration of ATP made the diagnosis more precise. Adverse reactions were seen in 75% of patients. There was a case of cardiac asystole, 50 sec long, with symptoms of clinical death. The sick sinus syndrome and atrioventricular block are regarded as a contraindication for bolus administration of ATP due to binodal dysfunction induced by the agent.
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