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  • Title: Use of antibiotic-PMMA beads in the ischemic foot.
    Author: Calhoun JH, Klemm K, Anger DM, Mader JT.
    Journal: Orthopedics; 1994 May; 17(5):453-7; discussion 458. PubMed ID: 8036189.
    Abstract:
    Thirty-six patients with 44 ischemic foot infections were managed with antibiotic-polymethylmethacrylate (PMMA) beads. Most of these patients received gentamicin-impregnated PMMA beads but tobramycin and vancomycin-impregnated PMMA beads were used on three patients. Angiopathy occurred in 35 patients secondary to diabetes and secondary to renal disease in 2; 1 patient had both diabetes and renal disease. The most common bacteria was Staphylococcus aureus (82%), although other organisms and multiple bacteria were present. In spite of the variability of the bacteria, PMMA beads were helpful in managing foot infections in this difficult patient population.
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