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  • Title: Toxicology and pharmacological action of anabaena flos-aquae toxin.
    Author: Carmichael WW, Biggs DF, Gorham PR.
    Journal: Science; 1975 Feb 14; 187(4176):542-4. PubMed ID: 803708.
    Abstract:
    Calves, rats, ducks, and goldfish given lethal oral doses of bacteria-free lyophilized cell suspensions of toxic Anabaena flos-aquae died as a result of respiratory arrest. Experiments with selected animals and pharmacological preparations showed that the main effect of the toxin was production of a sustained postsynaptic depolarizing neuromuscular blockade.
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