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  • Title: [Comprehensive evaluation of the effectiveness of antibiotics in experimental typhus infection].
    Author: Plekhanova TM, Lazarenko VN, Ruchko VM.
    Journal: Antibiot Khimioter; 1993; 38(8-9):51-5. PubMed ID: 8037579.
    Abstract:
    The informative indices of antibiotic efficacy in the treatment of typhus were determined in experiments on guinea pigs and used for the design of an integral index of a drug prophylactic activity against Rickettsia prowazekii. A procedure for a comprehensive estimation of an antibiotic prophylactic efficacy in experimental typhus by the whole complex of clinical, immunological and rickettsiological properties is described.
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