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  • Title: Benign cephalic histiocytosis: case report and literature review.
    Author: Peña-Penabad C, Unamuno P, Garcia-Silva J, Ludeña MD, Armijo M.
    Journal: Pediatr Dermatol; 1994 Jun; 11(2):164-7. PubMed ID: 8041659.
    Abstract:
    A 3-year-old boy had maculopapules on his face and neck since age 6 months. These were yellow-brown, asymptomatic, and clinically similar to flat warts. Histopathologic study revealed a fibrohistiocytic infiltrate in the superficial dermis. Ultrastructurally, comma-shaped bodies, desmosome-like junctions, and coated vesicles were seen; there were no lipid droplets or Birbeck granules. With these data, a diagnosis of benign cephalic histiocytosis was made. Twenty-five cases are reported in the literature: 17 males and 8 females (male:female ratio 2:1). Sixteen patients had lesions on parts of the body other than the head, neck, and shoulders.
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