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  • Title: Cogwheel rigidity related to lithium maintenance.
    Author: Shopsin B, Gershon S.
    Journal: Am J Psychiatry; 1975 May; 132(5):536-8. PubMed ID: 804258.
    Abstract:
    Neurological examinations of 27 outpatients receiving lithium carbonate maintenance therapy for recurrent affective illness revealed that most of the patients receiving lithium for more than 8 months had cogwheel rigidity. The data suggest a positive correlation between the duration of lithium maintenance and the severity of cogwheeling. Intravenous administration of benztropine, an antiparkinsonian drug, did not abolish or significantly ameliorate this symptom.
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