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  • Title: Synthesis and anticancer activity of new phenyl-ring substituted 4-morpholino-1-phenylthio-2-butanones [Mannich bases].
    Author: Siatra-Papastaikoudi T, Tsotinis A, Chinou I, Roussakis C.
    Journal: Farmaco; 1994 Mar; 49(3):221-3. PubMed ID: 8043174.
    Abstract:
    The preparation of phenyl-ring substituted 4-morpholino-1-phenylthio-2-butanones 4a-e is described. These compounds were evaluated against P-388 leukemia and human cancer rhinopharynx KB cells in vitro; some compounds were found to exhibit activity against these cell lines.
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