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  • Title: [Effects of N-acetylasparaginic acid during frontal lobectomy in the rat: antiamnestic action and effect on monoamine level].
    Author: Grekhova TV, Romanova GA, Gaĭnetdinov RR, Kudrin VS, Raevskiĭ KS.
    Journal: Biull Eksp Biol Med; 1993 Feb; 115(2):159-61. PubMed ID: 8043794.
    Abstract:
    Effects of N-acetyl-aspartic acid (NAA) on the behaviour models "open field", passive avoidance test and content of monoamines and their metabolites in the brain areas on the 9-th day after frontal decortication were studied. NAA (50 mg/kg), i.p., daily, 9 days) exerted antiamnestic effect in decorticated rats, evaluated in passive avoidance test. Corresponding changes in concentration of serotonin and 5-hydroxyindolacetic acid in the brain of decorticated rats were also seen.
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