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  • Title: Repetitive and compulsive behavior in frontal lobe degenerations.
    Author: Ames D, Cummings JL, Wirshing WC, Quinn B, Mahler M.
    Journal: J Neuropsychiatry Clin Neurosci; 1994; 6(2):100-13. PubMed ID: 8044031.
    Abstract:
    The authors review the relationship of repetitive behaviors to frontal lobe degenerations and report the repetitive and compulsive behaviors, radiologic imaging findings, and neuropathology of 3 patients with dementia secondary to frontal lobe degeneration. These 3 patients and 78% of 46 proven pathologic cases of frontal lobe degeneration described in the literature demonstrate repetitive behaviors ranging from motor stereotypies to complex obsessive-compulsive disorder. This review suggests that combined damage to the frontal lobe, caudate nucleus, and globus pallidus may account for the repetitive behaviors seen in frontal lobe degenerations, idiopathic obsessive-compulsive disorder, and other neuropsychiatric diseases.
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