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  • Title: [Study of clinical pathology and discussion of surgical strategy in comprehensive mitral valvuloplasty].
    Author: Liu WY, Yang JX, Zhang WD.
    Journal: Zhonghua Wai Ke Za Zhi; 1994 Jan; 32(1):4-7. PubMed ID: 8045201.
    Abstract:
    The results of clinical pathologic study of 162 mitral valves (MV) intraoperatively and pathologic anatomy of 8 excised MV were reported. Type I 64 cases, type II 23 cases and type III 75 cases. The pathogenic causes were congenital heart disease in 22 cases degeneration in 27 cases infective endocarditis in 1 case and rheumatic disease in 112 cases. Of the excised MV, 7 rheumatic lesion with type III. All valve components were involved. The valve leaflets thickened significantly and valve orifice changed like a funnel or semi-funnel shape. Under light microscope there was no interface between the increased collagen fibers and the valve tissue. Some superficial collagen fibers appeared hyalinosis. The calcification, local necrosis and inflammatory cell infiltration could be seen in some cases but the rheumatic bodies and the chordae tendineae wrapped up in the thickened valve tissue only in one case respectively degenerative lesion with thin chordae tendineae which appeared muco-hyalinosis and ruptured in three points. According to the clinical pathology of MV the indication and surgical technique are discussed.
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