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  • Title: The medullary rostral ventrolateral pressor region: an electrophysiological study in decerebrate rat.
    Author: Frugière A, Barillot JC.
    Journal: Neurosci Lett; 1994 Mar 14; 169(1-2):191-4. PubMed ID: 8047281.
    Abstract:
    Decerebrate rat was used to study the discharge pattern of barosensitive neurons. This preparation avoids general anesthesia and suppresses painful sensations of the animal. Twenty-eight spontaneously active units were recorded in the rostral ventrolateral region of the medulla (RVLM). Six units had projections to the spinal cord (bulbospinal) and 22 were not antidromically activated by spinal cord stimulation (NAA). Transient hypertension induced by intravenous injection of noradrenaline depressed the activity of 21 units, and increased activity of 7, regardless of axonal destination. Unlike anesthetized rat, the decerebrate rat possesses spontaneously active neurons with excitatory response to hypertension.
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