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Pubmed for Handhelds

PUBMED FOR HANDHELDS

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  • Title: Clinical and histological features of 'mechanic's hands' in a patient with antibodies to Jo-1--a case report.
    Author: Mitra D, Lovell CL, Macleod TI, Tan RS, Maddison PJ.
    Journal: Clin Exp Dermatol; 1994 Mar; 19(2):146-8. PubMed ID: 8050145.
    Abstract:
    The clinical and histological features of 'mechanic's hands' are described in a patient with polymyositis characterized serologically by antibodies to histidyl tRNA synthetase (Jo-1). Although described in the past in association with polymyositis, these distinctive cutaneous lesions have only recently been associated with the 'anti-synthetase syndrome'. It is becoming apparent that recognition of subsets within the spectrum of polymyositis/dermatomyositis characterized by certain clinical and serological features not only have prognostic significance, but also may provide insights into mechanisms of disease.
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