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  • Title: Schistosoma mansoni: the presence of schistosomule-like characteristics in irradiated cercariae.
    Author: Yssel E, Wolmarans CT.
    Journal: Folia Parasitol (Praha); 1994; 41(1):45-50. PubMed ID: 8050755.
    Abstract:
    Schistosoma mansoni (Puerto Rican strain) cercariae were exposed to 10, 20, 50, 100, 200, 300, 400 and 500 krad gamma radiation from 60Co gamma source. From 10-100 krad irradiation no differences could be found in the behaviour of the cercariae when compared to the controls. From 200-500 krad there was an increase in mortality as well as in the number of cercariae that shed their tails. The Con A binding studies also performed on cercariae radiated with up to 100 krad indicate a direct relationship between the number of cercariae that bind Con A and radiation dose. All live cercarial heads collected after radiation also bound Con A. It thus seems possible that irradiation may act as a stimulus for cercariae to transform to schistosomulae.
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