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  • Title: Loss of sensitivity to low concentrations of NaCl following bilateral chorda tympani nerve sections in rats.
    Author: O'Keefe GB, Schumm J, Smith JC.
    Journal: Chem Senses; 1994 Apr; 19(2):169-84. PubMed ID: 8055266.
    Abstract:
    A reliable short-term NaCl taste test was developed for rats which resulted in differential responding to a variety of concentrations. The rats were required to exist on a low sodium diet for 8-10 days prior to the initiation of testing. The peak response in this test was to isotonic NaCl with lesser responding to hyper- and hypotonic solutions. After stable responding was obtained, bilateral sections were made of the chorda tympani nerves. This surgery resulted in a loss of sensitivity to the lowest hypotonic solutions (0.03 and 0.06 M NaCl). Little, if any, effect was noted in the perception of sucrose following these nerve sections.
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