These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: Evaluation of the nucleolar organizer region associated proteins in oral squamous cell carcinoma.
    Author: Epivatianos A.
    Journal: Ann Dent; 1994; 53(1):33-6. PubMed ID: 8060107.
    Abstract:
    Silver-binding nucleolar-organizer regions (AgNORs) were counted in sections from formalin-fixed, paraffin embedded blocks of oral squamous cell carcinoma. Twenty-four cases were histologically classified as grade 1 and fourteen cases as grade 2. In counting AgNORs two specifications were used. The mean number of AgNORs/nucleus (mAgNORs) was used as indicator of the DNA content and the percentage of tumor cells containing five or more AgNORs/nucleus (pAg-NORs) as indicator of the proliferative activity. These counts were examined with respect to their relation to the histologic grading. The pooled mean counts were: Grade 1 carcinomas mAgNORs 4.73 +/- 1.04 and pAgNORs 49.87 +/- 23.41 (mean +/- SD); Grade 2 carcinomas mAgNORs 7.04 +/- 0.95 and pAgNORs 79.14 +/- 20.14. The differences of these results between grade 1 and 2 were statistically significant. These data possibly indicate that in grade 2 oral squamous cell carcinoma there is a higher DNA content and proliferative activity of the tumor cells than in grade 1.
    [Abstract] [Full Text] [Related] [New Search]