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  • Title: Humoral immune response to the Trypanosoma cruzi complement regulatory protein as an indicator of parasitologic clearance in human Chagas' disease.
    Author: Norris KA, Galvão LM, Schrimpf JE, Cançado JR, Krettli AU.
    Journal: Infect Immun; 1994 Sep; 62(9):4072-4. PubMed ID: 8063427.
    Abstract:
    Immunoprecipitation of the purified 160-kDa complement regulatory protein of Trypanosoma cruzi by Chagas' disease patient sera was examined as a possible correlate of the complement-mediated lysis test and as an indicator of parasite clearance. The results presented demonstrate that assessment of the humoral response to this antigen is a useful indicator of parasite clearance and may be particularly helpful in the assessment of some patients for whom other serological tests produce ambiguous results.
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