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  • Title: Gastric relaxation in response to chemical stimulation of the area postrema in the rabbit.
    Author: Bongianni F, Mutolo D, Srinivasan M, Staderini G, Baccari MC, Calamai F, Pantaleo T.
    Journal: Brain Res; 1994 May 23; 646(2):307-11. PubMed ID: 8069679.
    Abstract:
    Microinjections of DL-homocysteic acid into the area postrema (AP) of anesthetized rabbits provoked gastric relaxations associated with small changes in blood pressure and marked excitatory effects on respiration. Both gastric and cardiovascular effects failed to occur after bilateral vagotomy. Comparable gastric relaxations were induced before and after treatment with atropine or atropine and guanethidine. The AP appears to play a role in gastric motility via vagus nerves and nonadrenergic noncholinergic intramural inhibitory neurons.
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