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  • Title: Studies on stimulation and properties of antiglobulin antibodies. I. Influence of heatig at 56 degrees C and 60 degrees C on antigenicity.
    Author: Dudziak Z, Panek G, Feluś E, Nolewajka E, Kapp-Burzyńska Z, Achtelik W, Hendryk S.
    Journal: Arch Immunol Ther Exp (Warsz); 1975; 23(2):201-5. PubMed ID: 807178.
    Abstract:
    The autoimmunogenic properties of whole rabbit serum heated at 56 degrees C and 60 degrees C were studied in rabbits. Autologous rabbit serum heated 20 min at 60 degrees C was immunogenic. The state of induced immunity manifested itself by the appearance of antibodies to antigens of heterologous sera: human, goat and guinea pig. No antibodies for autologous sera were found, including autologous sera heated 20 min at 60 degrees C. The antibodies for heterologous sera directed against gamma-globulins were detected by the passive hemagglutination test and by precipitation in agar gel.
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