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  • Title: [Buspirone: a new possibility in the treatment of anxiety].
    Author: Faludi G.
    Journal: Orv Hetil; 1994 Aug 14; 135(33):1807-13. PubMed ID: 8072756.
    Abstract:
    Buspiron an azaspirodecanedione, heterocyclic compound which, although structurally unrelated to the benzodiazepines, possesses comparable anxiolytic activity. Because buspirone lacks hypnotic, anticonvulsant and muscle relaxant properties, it has been termed "anxioselective". It seems unlikely to generate the problems of dependence, abuse and rebound. It does not impair psychomotor or cognitive performance and appears to have no additive effect with other CNS-active agents, particularly alcohol. Clinical trials and studies of buspiron suggest that it is an effective treatment for the relief of symptoms of anxiety, especially in patients in whom daytime alertness is particularly important.
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