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  • Title: [A plasmid-mediated SHV type extended-spectrum beta-lactamase in Beijing isolate of Enterobacter gergoviae].
    Author: Cheng Y, Li Y, Chen M.
    Journal: Wei Sheng Wu Xue Bao; 1994 Apr; 34(2):106-12. PubMed ID: 8073758.
    Abstract:
    By conjugation experiment, an extended-spectrum beta-lactamase (ESb1a) encoded on a transferable plasmid of approximately 60 Kilobases was found in a clinical strain of Enterobacter gergoviae isolated from Peking Union Medical College Hospital. Its E. coli transconjugant was resistant to all beta-lactams tested except cefoxitin and imipenem. Clavulanic acid, a classical beta-lactamase inhibitor, inhibited its activity. Hybridization with an intragenic probe for SHV-1 revealed that this ESb1a may be related to, or derived from SHV enzyme.
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