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Title: Case report: cutaneous manifestations of cryptococcosis. Author: Haight DO, Esperanza LE, Greene JN, Sandin RL, DeGregorio R, Spiers AS. Journal: Am J Med Sci; 1994 Sep; 308(3):192-5. PubMed ID: 8074140. Abstract: Cutaneous cryptococcosis usually is associated with concurrent systemic infection and actually may develop before clinical manifestations of cryptococcal meningitis become apparent. It is rare for a cryptococcal infection to be localized only to the skin. A case of cutaneous cryptococcosis is described in an immunocompromised patient who initially had a rash and a positive serum cryptococcal antigen titer, but no central nervous system involvement. The papular pustular skin lesions disappeared after 8 weeks of therapy with amphotericin B, which was stopped secondary to progressive azotemia. Less than 2 months after therapy, the skin lesions recurred, again without evidence of systemic disease. Treatment with oral fluconazole resulted in a gradual resolution of the cutaneous lesions. The pathogenesis of cryptococcosis is discussed, with emphasis on the management of cutaneous cryptococcosis.[Abstract] [Full Text] [Related] [New Search]