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  • Title: A radioimmunoassay for rat serum parathyroid hormone using N-terminal of PTH.
    Author: Fujita T, Okano K, Ohata M, Yoshikawa M.
    Journal: Endocrinol Jpn; 1975 Apr; 22(2):159-62. PubMed ID: 807470.
    Abstract:
    Partially purified bovine parathyroid hormone (PTH) produced two kinds of antisera, GP-100 reacting with 125I-labeled bovine PTH (b-PTH 1-84) alone and GP-M reacting with 125I-labeled synthetic N-terminal portion of bovine PTH (b-PTH 1-34) as well as b-PTH 1-84. Rat serum PTH reacted with the latter but not in the former, suggesting a similarity to b-PTH 1-34. Rat serum PTH became undetectable after parathyroidectomy, and increased after Na2-EDTA injection and following renal injury with sodium sulfacetylthiazole.
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