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  • Title: [Multi-variate analysis of prognostic factors in gastric cancer with Cox' proportional hazard model].
    Author: Nakajima T, Ota K, Ishihara S, Wakabayashi K, Nishi M.
    Journal: Gan To Kagaku Ryoho; 1994 Aug; 21(11):1768-74. PubMed ID: 8080294.
    Abstract:
    A total of 8,993 cases of gastric cancer which were undergone gastrectomy at Cancer Institute Hospital, Tokyo were subjected to the multi-variate analysis of prognostic factors in gastric cancer. Relative ratio of hazard risk indicated the rank of importance in prognostic factors as the following order: Hepatic metastasis, radicality of surgery, macroscopic tumor type, serosal involvement, number of involved lymph node, and grade of lymph node metastasis. Difference in the results of analysis was observed between mono- and multi-variate analysis in the following categories: site of primary lesion, type of resection, and chemotherapy. These results suggested the importance of multimodality therapy to achieve the absolute curative surgery for advanced cancer, and also the importance of multi-variate analysis for the proper evaluation of prognostic factors.
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