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  • Title: Anti-HIV agents. III. Synthesis and in vitro anti-HIV activity of novel 1H,3H-thiazolo[3,4-a]imidazo[4,5-b]pyridines.
    Author: Chimirri A, Grasso S, Montforte AM, Monforte P, Zappalà M.
    Journal: Farmaco; 1994 May; 49(5):345-8. PubMed ID: 8080617.
    Abstract:
    The one-pot synthesis of 1H,3H-thiazolo[3,4-a]imidazo[4,5-b]pyridines is described. The antiviral activity against human immunodeficiency virus (HIV) of the compounds obtained was explored: 1-(2',6'-dichlorophenyl) (5g) and 1-(2',6'-difluorophenyl)-1H,3H-thiazolo- [3,4-a]imidazo[4,5-b]pyridine (5h) exhibit reproducible in vitro anti-HIV activity.
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