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  • Title: Therapeutic interaction of lamotrigine and sodium valproate in intractable myoclonic epilepsy.
    Author: Ferrie CD, Panayiotopoulos CP.
    Journal: Seizure; 1994 Jun; 3(2):157-9. PubMed ID: 8081644.
    Abstract:
    The clinical and EEG features of a 13-year-old girl with an unusual refractory myoclonic epilepsy is presented. Control was achieved only when lamotrigine was combined with sodium valproate. This may represent a specific pharmacodynamic interaction between these drugs with implications for therapy in the generalized epilepsies.
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