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  • Title: Localized pleural mesothelioma with elevation of high molecular weight insulin-like growth factor II and hypoglycemia.
    Author: Sakamoto T, Kaneshige H, Takeshi A, Tsushima T, Hasegawa S.
    Journal: Chest; 1994 Sep; 106(3):965-7. PubMed ID: 8082393.
    Abstract:
    Recurrent hypoglycemia occurred in a 48-year-old woman with a localized pleural mesothelioma. During hypoglycemia, serum high molecular weight insulin-like growth factor II (IGF-II) was elevated. The tumor also contained a high level of high molecular weight IGF-II. We propose that the primary cause of the hypoglycemia in this patient was the high molecular weight IGF-II produced by the tumor.
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