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  • Title: [Prognostic significance of baseline state of platelet aggregation and blood viscosity during gravitational plasmapheresis in patients with angina pectoris].
    Author: Kirichenko LL, Radzevich AE, Koniakhin AIu.
    Journal: Kardiologiia; 1993; 33(2):53-6. PubMed ID: 8084132.
    Abstract:
    The study was undertaken to examine 56 patients (mean age 54.9 +/- 1.1 years) who had functional class III (n = 12), IV (n = 32), and unstable (n = 12) angina pectoris. Due to inefficacy of conservative therapy, all the patients underwent gravitation plasmapheresis (GPA). The parameters of induced platelet aggregation were examined by the Born-O'Brien method and blood viscosity on a rotor viscometer before, immediately and on days 1 and 3 after GPA. It was found that the baseline blood viscosity and platelet aggregation should be known to predict the natural history of angina in the following 1-3 days after GPA. There was a pronounced positive clinical effect in higher blood viscosity and platelet aggregation. An improvement in the clinical course of the disease and its stabilization were not observed in the baseline lower blood viscosity and platelet in patients with progressive angina.
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