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  • Title: [Long-lasting afterhyperpolarization of sympathetic preganglionic neurons of neonate rat spinal cord slices].
    Author: Wang MY.
    Journal: Sheng Li Xue Bao; 1994 Feb; 46(1):95-9. PubMed ID: 8085176.
    Abstract:
    Intracellular recordings of antidromically identified sympathetic preganglionic neurons (SPNs) were made in thoracolumbar spinal cord slices from neonate rats (7-16 days). In the SPNs population, a 7-20 mV long-lasting afterhyperpolarization (11-AHP) lasting for 1 to 10 s following spike potential could be recorded in part of the neurons and the 11-AHPs was usually preceded by a fast component lasting shorter than 400 ms. With decrease of membrane resistance during 11-AHP, membrane potential-dependent property was observed and the calculated reversal potential was -90 to -100 mV. The results indicate that the 11-AHPs are effective in the control of firing frequency of SPNs.
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