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  • Title: Chemistry of technetium radiopharmaceuticals. I. Exploration of the tissue distribution and oxidation state consequences of technetium (IV) in Tc-Sn-gluconate and Tc-Sn-EHDP using carrier 99Tc.
    Author: Hambright P, McRae J, Valk PE, Bearden AJ, Shipley BA.
    Journal: J Nucl Med; 1975 Jun; 16(6):478-82. PubMed ID: 808594.
    Abstract:
    The distribution in rats of the renal agent Tc-Sn-gluconate using both 99mTc and carrier amounts of 99Tc was similar. The same behavior was shown with the bone agent Tc-Sn-EHDP. The radiopharmaceutical consequences of the observed Tc(IV) oxidation state in these systems are explored.
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