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  • Title: Adrenal adenomas: characteristic hyperintense rim sign on fat-saturated spin-echo MR images.
    Author: Ichikawa T, Ohtomo K, Uchiyama G, Koizumi K, Monzawa S, Oba H, Nogata Y, Kachi K, Toyama K, Yamaguchi M.
    Journal: Radiology; 1994 Oct; 193(1):247-50. PubMed ID: 8090900.
    Abstract:
    PURPOSE: To determine whether adrenal adenomas can be differentiated from metastases on fat-saturated magnetic resonance (MR) images. MATERIALS AND METHODS: Twenty-eight adrenal adenomas and 20 metastatic lesions were imaged at 1.5 T by means of fat-saturated T1- and T2-weighted and gadolinium-enhanced T1-weighted sequences. The authors evaluated visually whether structures of high signal intensity (hyperintense rim sign) could be observed in the outer margin of the adrenal masses. RESULTS: Twenty-six of 28 adrenal adenomas revealed the hyperintense rim sign on at least one kind of fat-saturated image, compared with only one of 20 metastases. The sensitivity of the hyperintense rim sign as suggestive of adrenal adenoma was 92%, specificity was 95%, and overall accuracy was 94%. CONCLUSION: The hyperintense rim sign is characteristic of adrenal adenomas. Thus, adrenal adenomas can be differentiated from metastases by means of this new imaging sign on fat-saturated MR images.
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