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  • Title: Investigation of an outbreak of hepatitis A in Irish haemophilia A patients.
    Author: Lawlor E, Johnson Z, Thornton L, Temperley I.
    Journal: Vox Sang; 1994; 67 Suppl 1():18-9; discussion 20. PubMed ID: 8091729.
    Abstract:
    Since 1990, Irish haemophilia A patients have been treated with solvent-detergent(SD)-treated virally inactivated high-purity factor VIII concentrate prepared from plasma from Irish voluntary non-remunerated donors. In 1992, 13 haemophilia A patients developed clinical hepatitis A and a further 17 patients showed serological evidence of recent infection by hepatitis A. All but 3 of these patients had had recent exposure to SD-treated product. A case-control study is underway to determine whether these cases represent transmission through product or environmentally acquired hepatitis A.
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