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Title: [Karyometric analysis of pathologic changes in follicular cells of the thyroid gland]. Author: Kirillov VA, Iushchenko IuP, Demidchik EP. Journal: Arkh Patol; 1994; 56(3):65-8. PubMed ID: 8092946. Abstract: Using cytometry it is shown, that distribution histograms of the values of follicular cell nuclear areas depend upon the nature of the thyroid disease. Dome-like distribution was observed in follicular and papillary cancer, while for follicular adenoma as well as for nodular colloid and diffuse toxic goiter or for autoimmune thyroiditis exponential-like dependence was typical. Distribution histograms under normal conditions had the form of a column. The phenomena observed can be used as an additional diagnostic criterion of malignant transformation of thyroid follicular cells.[Abstract] [Full Text] [Related] [New Search]