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  • Title: The neurobiological basis of mixed depression-anxiety states.
    Author: Gulley LR, Nemeroff CB.
    Journal: J Clin Psychiatry; 1993 Jan; 54 Suppl():16-9. PubMed ID: 8093884.
    Abstract:
    A recognition of the clinical overlap of symptoms of anxiety disorders and those of affective disorders has brought with it a need to move beyond descriptive definitions of the syndromes to an etiologic and neurobiological understanding of their psychopathology. The authors discuss the neurobiological basis of mixed depression-anxiety states with special attention to the literature on pharmacologic treatment outcome studies, neurotransmitters in anxiety and depression, and the hypothalamic-pituitary-adrenal axis.
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