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  • Title: Marine antitumor agents: 14-deoxycrassin and pseudoplexaurol, new cembranoid diterpenes from the Caribbean gorgonian Pseudoplexaura porosa.
    Author: Rodríguez AD, Martínez N.
    Journal: Experientia; 1993 Feb 15; 49(2):179-81. PubMed ID: 8095027.
    Abstract:
    Two new cytotoxic antitumor diterpenoids of the cembrane class, named 14-deoxycrassin (3) and pseudoplexaurol (4), have been isolated from the Caribbean gorgonian octocoral Pseudoplexaura porosa. The structure of lactone 3, possessing the infrequently encountered alpha-methylene-delta-lactone ring, has been established from spectral and chemical data and that of alcohol 4 has been established from spectral data.
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