These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


Pubmed for Handhelds

PUBMED FOR HANDHELDS

Search MEDLINE/PubMed

  • Title: [Blood-CSF kinetics of penicillin G in neurosyphilis (author's transl)].
    Author: Ritter G, Volles E, Müller F, Nabert-Bock G.
    Journal: MMW Munch Med Wochenschr; 1975 Aug 29; 117(35):1383-6. PubMed ID: 809679.
    Abstract:
    Measurements of the penicillin concentration in serum and cerebrospinal fluid patients with neurosyphilis showed that conventional therapy can attain effective treponemocidal levels for only a short time or not at all in the CSF and brain-tissue, the regions where the treponemas are found in this particular stage of disease. Intravenous infusions with high doses (0,5 mega unit penicillin-G/kg body weight in 24 hours) over more than one generation phase of the treponemas (35-43 hours) considerably improve the recovery. 16 patients were treated in this way and been followed over 2-3 years clinically and immunologically.
    [Abstract] [Full Text] [Related] [New Search]