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Title: High frequency intergenomic recombination of suid herpesvirus 1 (SHV-1, Aujeszky's disease virus). Author: Christensen LS, Lomniczi B. Journal: Arch Virol; 1993; 132(1-2):37-50. PubMed ID: 8102524. Abstract: Examples are given of observations made with field isolates of suid herpesvirus 1 (SHV-1) which indicate that intergenomic recombination is a common phenomenon associated with the virus. This was further confirmed by experimental co-infection of a pig with 2 virus strains with different, stable and easily identifiable genomic markers, followed by natural transmission to a group of contact pigs. A variety of recombinants was subsequently isolated, while none of the parental strains were re-isolated from any of the pigs. It is suggested that co-invasion of cells and recombination between viral genomes play a role in the life cycle of the virus.[Abstract] [Full Text] [Related] [New Search]