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  • Title: [Action of an antioxygen food additive, di-tertio-butyl-hydroxy-toluene on the electron transport and on the coupling of oxidation and phosphorylation in the liver mitochondria of rats].
    Author: Pascal MG, Tennoine T.
    Journal: C R Acad Hebd Seances Acad Sci D; 1975 Apr 21; 280(15):1833-6. PubMed ID: 810260.
    Abstract:
    BHT in vitro has a strong uncoupling effect on phosphorylating oxidations of hepatic mitochondria at concentrations less than or equal to 2.5.10(-4) M. On the contrary, no uncoupling is found after in vivo administration of 0.5% of BHT in rat diet. The differences between in vitro and in vivo results are discussed.
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