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  • Title: [The effect of mast cells on the T-lymphocyte mechanisms of hemopoiesis regulation in inflammation].
    Author: Gol'dberg ED, Dygaĭ AM, Klimenko NA, Gumilevskiĭ BIu, Bogdashin IV, Sherstoboev EIu.
    Journal: Biull Eksp Biol Med; 1993 Jun; 115(6):602-4. PubMed ID: 8104049.
    Abstract:
    It was shown on the model of acute infections peritonitis in mice that the inflammation induced in the absence of mast cells was characterized by increased T-lymphocyte accumulation and macrophage-activating factor production and, in case of Thy-1,2(+)-lymphocyte elimination from bone marrow cell suspension, by earlier suppression of colony-stimulating and erythropoietic activity production by adhering and non-adhering myelokaryocytes. The results indicate that the modulatory effect of mast cells on haematopoiesis in inflammation is due in many respects to T-lymphocyte inhibition.
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