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  • Title: Influence of 1,3-di-o-tolylguanidine and rimcazole, selective sigma ligands, on apomorphine and neuroleptic effects.
    Author: Maj J, Rogóz Z, Skuza G.
    Journal: Pol J Pharmacol; 1993; 45(3):327-30. PubMed ID: 8106091.
    Abstract:
    1,3-di-o-tolylguanidine and rimcazole act as typical neuroleptics (antagonize the apomorphine-induced aggression and climbing) and at the same time, as dopamine stimulants (antagonize neuroleptic-induced catalepsy). When given alone, they exhibit no visible behavioral effects.
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