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  • Title: Asymptomatic neurosyphilis after doxycycline therapy for early latent syphilis.
    Author: Zenilman JM, Rand S, Barditch P, Rompalo AM.
    Journal: Sex Transm Dis; 1993; 20(6):346-7. PubMed ID: 8108759.
    Abstract:
    A 50-year-old woman allergic to penicillin with early latent syphilis was treated with two courses of doxycycline. Ten months after diagnosis, she had no evidence of serologic response. A lumbar puncture demonstrated asymptomatic neurosyphilis. Penicillin desensitization was performed and she was successfully treated. This case re-emphasizes the need for close serologic follow-up in patients with latent syphilis.
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