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  • Title: Speed of onset of sensory block for elective extradural caesarean section: choice of agent and temperature of injectate.
    Author: Clark V, McGrady E, Sugden C, Dickson J, McLeod G.
    Journal: Br J Anaesth; 1994 Feb; 72(2):221-3. PubMed ID: 8110578.
    Abstract:
    We have studied the effects of choice of local anaesthetic and temperature of extradural injectate on speed of onset of sensory block for elective extradural Caesarean section in a double-blind trial in 120 women allocated randomly to one of four groups to receive either plain 0.5% bupivacaine or 2% lignocaine with 1:200,000 adrenaline at either room temperature or 38 degrees C. The onset time of lignocaine with adrenaline was shorter than that of bupivacaine regardless of temperature (P < 0.01). Warmed lignocaine produced the most rapid block overall (P < 0.025). The incidence of hypotension, ephedrine requirement, shivering, quality of analgesia and additional analgesic requirements were similar for all groups.
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