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  • Title: [Increase of immune response by administration of metabolizable vegetable oil emulsions].
    Author: Audibert F, Chedid L.
    Journal: C R Acad Hebd Seances Acad Sci D; 1975 Apr 07; 280(13):1629-32. PubMed ID: 811378.
    Abstract:
    Though highly efficient, Freund's adjuvant has serious limitations because it contains mineral oil and isomannide monooleate emulsifier (arlacel A). The present study describes the conditions under which a stable water in oil emulsion can be produced by using metabolizable peanut oil with arlacel. When mycobacteria are added, a potent emulsified oil adjuvant is obtained which increases the immune response to BSA and to influenza vaccine.
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