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  • Title: SLE-associated thrombocytopenia in pregnancy: successful outcome with combined IgG infusion and platelet transfusion.
    Author: Li EK, Li CY, Cohen MG.
    Journal: Br J Clin Pract; 1993; 47(6):338-9. PubMed ID: 8117561.
    Abstract:
    Autoimmune thrombocytopenia presents special problems during pregnancy because of the limited therapeutic options and the risks posed by even moderate degrees of thrombocytopenia. Although corticosteroids and intravenous immunoglobulin G (IV IgG) have been shown to be useful and relatively safe therapies, they are not always effective. We describe a patient with systemic lupus erythematosus (SLE) who developed severe thrombocytopenia unresponsive to prednisone and IV IgG. The combination of IV IgG and platelet transfusion immediately before delivery resulted in a rapid rise in platelet count and allowed a lower segment caesarean section to be undertaken without perioperative complication.
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