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  • Title: [The infectiousness of 18- to 20-kd proteins isolated from the brain of people who have died from amyotrophic leukospongiosis].
    Author: Poleshchuk NN, Kapitulets SP, Kapitulets NN, Kvacheva EB, Eremin VF, Votiakov VP.
    Journal: Biull Eksp Biol Med; 1993 Oct; 116(10):409-12. PubMed ID: 8117968.
    Abstract:
    Specific globular structures, 10-12 nm in diameter, having a high resistance to various physicochemical factors and infectivity have been isolated for the first time from the brain of 2 patients, who died of amyotrophic leukospongiosis (AL). It has been shown that these globules contain infectious major protease-resistant protein with a molecular weight of about 18-20 kD. The findings indicate the unique nature of a disease and they open new aspects of AL etiopathogenesis.
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