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  • Title: The study of histamine H1- and H2-receptors in human lung cancer.
    Author: Kondratenko TY, Zacharova IV, Katukov VYu, Kuzina NV, Severin ES, Kornilova ZCh, Perelman MI.
    Journal: Biochem Mol Biol Int; 1993 Nov; 31(3):399-404. PubMed ID: 8118413.
    Abstract:
    Data on human lung histamine H1- and H2-receptors in cancer and chronic inflammatory processes are reported. It has been found that the number of histamine H1-receptors significantly increases both in cancer and chronic pneumonia and does not practically change in tuberculosis lung parenchyma. The binding parameters of histamine H2-receptors both in cancer and inflammatory processes were similar to those obtained for the normal tissue. The important role of parenchymal histamine H1-receptors in the neuromodulation of airways in human lung adenocarcinoma is discussed.
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