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  • Title: Double-chambered right ventricle and Down's syndrome: a proposed new association.
    Author: Eltohami EA, Hajar HA, Folger GM.
    Journal: Angiology; 1994 Feb; 45(2):119-23. PubMed ID: 8129186.
    Abstract:
    Twenty-two cases of double-chambered right ventricle studied in detail from two different centers comprise the study population. Of these, 5 have trisomy-21 Down's syndrome; these five cases, comprising nearly 25% of the entire study group, were essentially evenly divided between the two centers. This unexpectedly high percentage of Down's syndrome associated with such an unusual cardiovascular malformation, albeit among a small population, is likened to the currently recognized and similar association of Down's syndrome and atrioventricular cushion deformities.
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