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  • Title: Effects of peripheral cold exposure on microvascular dynamics in systemic sclerosis.
    Author: Grassi W, Core P, Carlino G, Cervini C.
    Journal: Arthritis Rheum; 1994 Mar; 37(3):384-90. PubMed ID: 8129793.
    Abstract:
    OBJECTIVE: To determine the influence of cold exposure on microvascular permeability in systemic sclerosis (SSc). METHODS: Thirteen patients with SSc were studied by dynamic fluorescence videomicroscopy under basal conditions and after exposure to cold. RESULTS: Exposure to cold caused a significant reduction in the interstitial concentration of sodium fluorescein (P < 0.05 to 0.001). CONCLUSION: Our findings show that cold exposure has a striking effect on microvascular dynamics in SSc.
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